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This unique text presents a selection of innovative computational techniques to enable the efficient analysis of biological processes in large video sequences and databases. Features: provides a detailed introduction to the field of video bioinformatics; examines the analysis and visualization of injured brain tissue in rodent models, using magnetic resonance imaging and optical coherence tomography; discusses segmentation of stem cell colonies and analysis of individual stem cells; describes the application of commercially available software to solve problems in video bioinformatics related to stem cell behavior in vitro; reviews video bioinformatics problems in plant and fungus biology; presents a high throughput method for quantifying DNA damage in cells, and a method that uses optogenetics to regulate protein transport in cultured cells; surveys the various software tools and databases available for use with video bioinformatics problems.