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This text discusses the fundamental role played by qualitative change in economic development and the contribution made by technological change and innovation. This new examination of the actors and mechanisms of technological change focuses on changes in product technology and the evolution of organizations with special reference to their use of information and knowledge. Using an evolutionary framework, the author develops a model of technological evolution which explicitly introduces these key actors and mechanisms. An in-depth discussion of the present state of evolutionary theories focuses on their methodological foundations and applicability to learning in organizations.