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Typically, manuals of§pediatric hematology-oncology are written by specialists from high-income§countries, and usually target an audience with a sub-specialist level of§training, often assisted by cutting-edge diagnostic and treatment facilities.§However, approximately 80% of new cases of cancer in children appear in mid-§and low-income countries. Almost invariably, general practitioners or general pediatricians§without special training in oncology will look after children with malignancies§who enter the health care system in these countries. The diagnostic facilities§are usually limited, as are the treatment options. The survival figures in§these conditions are somewhere below 20%, while in high-income countries they§are in the range of 80% for many childhood cancers.§The§Practical Manual of Pediatric Hematology-Oncology is§the only book of its kind to provide specific guidance applicable to limited§resource settings and builds up from the foundation of general practitioner or§general pediatrician competence. Written and edited by leaders in the field,§this manual educates physicians on the essential components of the discipline,§filtered through the experience of specialists from developing countries, with§immediate applicability in the specific healthcare environment in these§countries.